Florida State Paramedic Practice Exam

How does Lasix primarily function in the treatment of heart failure?

1. Increases preload

2. Inhibits catecholamine actions

3. Decreases preload, prevents sodium reabsorption

4. Enhances calcium uptake in myocardial cells

The correct answer is: Decreases preload, prevents sodium reabsorption

Lasix, or furosemide, is a loop diuretic commonly used in the management of heart failure. Its primary mechanism of action involves decreasing preload and preventing sodium reabsorption, which plays a crucial role in alleviating the symptoms associated with heart failure. In heart failure, the heart's ability to pump blood effectively is compromised, often leading to fluid overload. This fluid retention increases preload, or the volume of blood returning to the heart, which can exacerbate the condition and cause symptoms such as swelling and shortness of breath. By promoting diuresis (increased urine production), Lasix leads to the removal of excess fluid from the body, which results in a reduction of blood volume and, consequently, a decrease in preload. Additionally, Lasix prevents sodium reabsorption in the renal tubules, primarily in the loop of Henle. By inhibiting the reabsorption of sodium, it further enhances diuresis and helps to lower blood pressure, contributing to the overall management of heart failure. This multifaceted approach aids in relieving the workload on the heart while improving symptoms and quality of life for patients with heart failure. The understanding of Lasix's role in heart failure management is critical for healthcare professionals to implement