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The spleen is primarily involved in what type of function?

  1. Hormonal regulation

  2. Blood filtration and immune response

  3. Fat digestion

  4. Calcium storage

The correct answer is: Blood filtration and immune response

The spleen plays a crucial role in the immune system and the filtering of blood, which is why blood filtration and immune response is the correct answer. The spleen's primary functions include the removal of old or damaged red blood cells from circulation and the recycling of iron and other components. It also serves as a site for the proliferation and activation of lymphocytes, which are essential for the immune response. In addition to filtering blood, the spleen monitors the blood for pathogens and helps to mount an immune response by producing antibodies and activating T-cells. Its unique structure allows it to act as a reservoir for blood as well, which can be important in cases of hemorrhage. The other options are less relevant to the function of the spleen. Hormonal regulation is primarily managed by glands such as the pancreas and thyroid. Fat digestion occurs mainly in the small intestine, with bile from the liver and enzymes from the pancreas aiding in the process. Calcium storage is primarily the function of bones rather than the spleen.