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Which side effect is associated with Verapamil?

  1. Hypotension

  2. Increased heart rate

  3. Dehydration

  4. Increased systemic resistance

The correct answer is: Hypotension

Verapamil is a calcium channel blocker that is primarily used to treat hypertension, angina, and certain arrhythmias. One of the main effects of Verapamil is vasodilation, which decreases systemic vascular resistance. As a result of this vasodilation, blood pressure can drop, leading to hypotension. This is an expected side effect and can manifest as dizziness or lightheadedness in patients who experience a significant drop in blood pressure. In contrast, the other options do not align with the pharmacological actions of Verapamil. Increased heart rate is typically not a side effect; rather, Verapamil tends to decrease heart rate due to its effect on the conduction system of the heart. Dehydration is not directly associated with Verapamil use and is more related to fluid management or other medications. Lastly, Verapamil works to decrease, not increase systemic resistance, due to its properties of promoting vasodilation.